SS-31 (Research-Grade Peptide)

Mitochondria-targeted tetrapeptide — for laboratory research only

Product Overview

SS-31 is a synthetic, cell-permeable tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) designed to selectively target the inner
mitochondrial membrane. It has been extensively investigated in preclinical and clinical research for its ability to
interact with cardiolipin, stabilize mitochondrial structure, and support efficient electron transport. SS-31 has been
studied in models of mitochondrial dysfunction, oxidative stress, and age-associated cellular decline. Supplied as a
high-purity lyophilized powder, this material is intended strictly for laboratory research use and is not approved for
human or veterinary administration.

Research Highlights

• Mitochondrial Targeting: SS-31 selectively localizes to mitochondria by binding cardiolipin, a
  phospholipid critical for inner mitochondrial membrane integrity and function.
  Proceedings of the National Academy of Sciences
• Oxidative Stress Research: Studies have shown SS-31 reduces mitochondrial reactive oxygen species (ROS)
  generation while preserving ATP production in cellular and animal models.
  Free Radical Biology & Medicine
• Age-Related Cellular Models: SS-31 has been investigated for its effects on mitochondrial efficiency
  in aging, muscle degeneration, and neurodegenerative disease models.
  Journal of Gerontology
• Ischemia & Metabolic Studies: Research has explored SS-31 in ischemia-reperfusion injury and metabolic
  stress models, highlighting its role in mitochondrial protection.
  Circulation Research

Product Details & Handling

• Synonyms: SS-31; Elamipretide; Bendavia
• Sequence: D-Arg-Dmt-Lys-Phe-NH₂
• Form: Lyophilized powder, supplied in sterile vials
• Purity: ≥ 98% (Certificate of Analysis provided)
• Storage: Store at –20 °C; protect from light and moisture
• Handling: For use only in controlled laboratory environments with appropriate PPE; consult SDS for safety information

Legal Disclaimer

This product is provided strictly for laboratory research use only.
It is not intended for human or veterinary consumption, therapeutic, diagnostic, or clinical application.
Customers are responsible for compliance with all applicable laws and institutional policies.
SS-31 is an investigational research compound and is not approved by the FDA as a drug, supplement, or treatment.
Windy City Peptide does not provide medical advice or support related to human use.